Research Lines

Laboratory Menu

RESEARCH LINES: The research of the Group focus on the development and application of omic sciences to Bioanalytical Chemistry and Environmental Analysis: chemical speciation and metallomics, metabolomics, proteomics (heteroatom tagged proteomics) and more recently metagenomics. The research lines are:

• Development of new analytical methods for sample preparation: miniaturized analytical techniques, membrane based analytical techniques (hollow fiber liquid phase microextraction-HF-LPME, pervaporation), and analysis: heteroatom tagged proteomics, metallomics, chemical speciation and metabolomics, instrumental couplings column switching methods.

• Environmental metallomics and metabolomics: Study of the biological response against pollutants in environmental bioindicators and laboratory models (mammals and invertebrates) combining heteroatom tagged proteomics and metabolomics. Antagonistic role of selenium and “chemical cocktails”.

• Influence of metals and selenium in the gut microbiota-brain axis: characterization using metagenomic techniques of gut microbiota in mammals exposed to pollutants and the connection with metals and chemical species in the body.

• The mother-offspring transfer of selenium, microbiota and pollutants: selenium (selenometabolites and selenoproteins) and other elements (toxic and essentials). Combination of metallomics, metabolomics and metagenomics for the study of the mother-offspring transfer at chemical and biological levels, that affects the development of the neurological and immune system of the offspring.

• Chemical speciation of selenium, arsenic, metals and heteroatom tagged proteomics in biomedicine: Study of metals and their chemical species in the onset and developmet of diseasess (Alzheimer´s disease, cancer, cardiovascular problems.

• Metabolomics in biomedicine: Lung cáncer and Alzheimer´s disease.

• Functional food, foodomics, chemical speciation and food safety: development of functional food and nutraceuticals enriched in selenium, study of the bioaccessibility and bioabvailability in mammals.